As a cursed detective struggles to contain the wolf within, he suspects he is being framed for murder. In order to uncover the true killer, he must accept the wolf? or be lost to the beast forever.

Sounds interesting. Though there's a lot of vague stuff here.
"cursed detective" - specific
"struggling to contain the wolf within" - vague
"suspects he is being framed" - vague
"framed for murder" - specific
"uncover the true killer" - specific
"accept the wolf...beast forever" - vague

So far I'm seeing "A werewolf detective framed for murder must...(need something specific).

Maybe the guy murdered was a working on a werewolf antidote thingy and so the only chance of getting his hands on this cure will be to unravel the mystery of his murder blah blah blah."

What did you have in mind?

adjective even... lol

That's tight, man. Your story including inner and outer conflict in 19 words. Extremely tight.

Since you have words to spare now, maybe you could intensify with an adverb (one of my passions) such as:

'A cursed detective ? framed for murder ? needs to accept the terrifying beast within in order to uncover the true killer...'

You could even add some inner freedom, from the 'curse' as well:

A cursed detective ? framed for murder ? needs to accept the beast within to uncover the true killer...and free himself from the curse forever?